Slay the Spire is a single-player game that combines card games and roguelikes. It was developed and published by Mega Crit Games and released on January 22, 2019. The game falls into the indie, strategy, and turn-based genres. Players can craft unique decks using hundreds of cards they discover while climbing the Spire.

The layout of the Spire changes with each attempt, offering players different paths to take, enemies to face, cards to find, relics to discover, and even bosses to fight. Powerful items called relics can be found throughout the Spire and have significant effects on gameplay.

Players who focus solely on completing the main story can expect to spend around 12 hours with the game. Those who also explore additional content can anticipate a playtime of 47 hours. A completionist playthrough, which involves experiencing all aspects of the game, will take approximately 194 hours.